What is it about?

MicroRNA let-7a is an important regulator in allergic airway diseases. We have shown for the first time that MicroRNA let-7a can regulate OPN expression in a mouse model of allergic rhinitis .

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Why is it important?

Our result shows the mechanism that MicroRNA let-7a uses for its biological function in allergic diseases.

Perspectives

I think the research is quite interesting and instructive. The result shows that MiRNAs like MicroRNA let-7a play an important role in allergic diseases. I hope you find this article thought-provoking and further investigate to find whether more and more useful MiRNAs in allergic rhinitis can be found in the future.

Yang Liu
Wuhan City Tongji Hospital Consortium

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This page is a summary of: MicroRNA let-7a up-regulates OPN expression in a mouse model of allergic rhinitis, The Journal of Laryngology & Otology, August 2017, Cambridge University Press,
DOI: 10.1017/s002221511700175x.
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