What is it about?

Propionibacterium thoenii P127 produces propionicin PLG-1, a bacteriocin that inhibits wide range of food-borne pathogens. We have isolated and sequenced the gene responsible for propionicin PLG-1 production. Such gene was transferred using pLEB590 food-grade cloning vector to some lactic acid bacterial (LAB) strains. LAB transformants showed an antimicrobial activity against some food-borne pathogens. So, they can be used in dairy industry to control food-borne pathogens.

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Why is it important?

plg-1 gene was isolated, sequenced, and cloned to lactic acid bacteria for the first time. LAB transformants can be used in dairy industry to control the food-borne pathogens that are largely distributed worldwide and to feed schoolchildren in the poor countries where dangerous epidemic diseases and diarrhea prevail.

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samehgene@yahoo.com

Dr Sameh Ezzat Mohamed
City for Scientific Research and Technological Applications

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This page is a summary of: The expression of propionicin PLG-1 gene (plg-1) by lactic starters, Journal of Dairy Research, February 2015, Cambridge University Press,
DOI: 10.1017/s0022029915000011.
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