What is it about?
The main objective of the present study was to determine the potential of n-3 and n-6 fatty acids or coenzyme Q10 (CoQ10) to alter serum prostate-specific antigen (PSA) levels in normal healthy men.
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Why is it important?
Prostate cancer (PCa) accounts for 28% of total cancer incidence and is the second most common cause of cancer related death of men in the USA. Prostate-specific antigen (PSA) testing is widely used for the detection of asymptomatic and early-stage PCa. There is great controversy surrounding PSA screening, because a considerable number of men with elevated serum PSA, who were referred for biopsy, were not diagnosed with PCa. Indeed, serum PSA concentrations be affected by many factors unrelated to prostate disease, including age, race, type 2 diabetes mellitus, dietary factors, certain clinical cardiac problems) and obesity. Consumption of some medications such as non-steroidal antiinflammatory drugs, acetaminophen and statin scan also affect serum PSA levels. In general, overall PCa mortality is high in Northern Europe and North America, and is low in Japan and other Asian nations(13). But, for Japanese migrants to the USA, the incidence of mortality increases as a function of the number of years lived in the USA. The major contributory factor thought to account for this increased frequency in PCa death is the Western diet.
Read the Original
This page is a summary of: Effects of EPA, γ-linolenic acid or coenzyme Q10 on serum prostate-specific antigen levels: a randomised, double-blind trial, British Journal Of Nutrition, November 2012, Cambridge University Press, DOI: 10.1017/s0007114512004783.
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