Detection of tetracycline and other antimicrobial residues in milk from cows with clinical mastitis treated by combination therapy

Aleksandar Siljanoski, Renata Ciglarič, Tomaž Pezdir, Petra R Lainšček, Jožica Dolenc, Jože Starič, Ksenija Šinigoj-Gačnik
  • Journal of Dairy Research, July 2018, Cambridge University Press
  • DOI: 10.1017/s0022029918000389

Antimicrobial residues in cows milk treated by combination therapy

What is it about?

Cows with clinical mastitis were included in the study. Cows were treated with combination of antimicrobial drugs (extra label use) for clinical mastitis on a commercial dairy farm. Antimicrobial residues were tested after the prescribed withdrawal period in milk from infected/treated and healthy udder quarters.

Why is it important?

Intramammarily treated mastitic cows with impaired health had high concentrations of antimicrobial residues in milk after the withdrawal period. After the prescribed withdrawal period residues of tetracycline, neomycine, cefquinome and cephalexin were still above the MRL in some cases. Milk from untreated healthy udder quarters had no antimicrobial residues two milkings before the prescribed withdrawal period.


ksenija Šinigoj Gačnik
University of Ljubljana, Veterinary Faculty

After intramammary treatment of cows with sever mastitis, we recommend longer withdrawal period, in order to prevent drug residue in bulk milk tanks.

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The following have contributed to this page: ksenija Šinigoj Gačnik