Is a single Xpert MTB/RIF enough to rule out pulmonary TB in hospitalized patients?
What is it about?
Hospitalized patients with suspected pulmonary TB need 2-3 AFB smears to be negative before they can be taken of airborne isolation. We wanted to see if a single negative PCR test (Gene Xpert MTB/RIF) that takes 2 hours could be used to shorten the duration of airborne isolation without missing any cases.
Why is it important?
Ruling out TB in patients in a low-incidence setting in the US can be time consuming and frustrating for patients and doctors. Maintaining and operating and negative pressure rooms for airborne isolation is expensive.
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