What is it about?
The earlier study identifying the replacement of the C-5 acetamido functional group with a triazolyl moiety as a bioisosteric replacement.
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Why is it important?
Further confirmation of the bioisosterism of the C-5 acetamido functional group with a triazolyl moiety
Perspectives
This study adds knowledge to the SAR of the oxazolidinone class of antibacterial agents.
Professor Oludotun A. Phillips
Kuwait University, Faculty of Pharmacy
Read the Original
This page is a summary of: Synthesis and antibacterial activity of 5-substituted oxazolidinones, Bioorganic & Medicinal Chemistry, January 2003, Elsevier,
DOI: 10.1016/s0968-0896(02)00423-6.
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