What is it about?

Agmatine is a natural dietary ingredient with superior neuroprotective properties. The study provides evidence showing that agmatine sulfate is not toxic at the cellular level.: It did not cause mutations in bacteria (using the Ames test). It did not cause changes in chromosomes (using a chromosomal aberration test with Chinese Hamster lung cells). And it lacked toxic effects on the cell nucleus following oral administration in mice.

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Why is it important?

Taken together with previously published data, results of the present study further support the safety of agmatine sulfate as a dietary ingredient.

Perspectives

The cumulative evidence now clearly indicates that the dietary ingredient agmatine sulfate can be generally regarded as safe under the conditions of its intended use as a food additive.

Dr Gad M. Gilad
Gilad&Gilad LLC

Read the Original

This page is a summary of: Evidence for safety of the dietary ingredient agmatine sulfate as assessed by mutagenicity and genotoxicity studies, Toxicology Reports, December 2024, Elsevier,
DOI: 10.1016/j.toxrep.2024.101720.
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