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Ethyl lactate as a bio based green solvent was used, for the first time to promote the 1,3-dipolar cycloaddition reactionwhich generates a series of medicinally privileged spiro[benzo[f]pyrrolo[2,1-a]isoindole-5,30-indoline]-20,6,11-trione derivatives.
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This page is a summary of: Ethyl lactate as a promising bio based green solvent for the synthesis of spiro-oxindole derivatives via 1,3-dipolar cycloaddition reaction, Tetrahedron Letters, July 2013, Elsevier,
DOI: 10.1016/j.tetlet.2013.05.035.
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