What is it about?

This article examines an approach never before considered for reducing the entry to the environment of active pharmaceutical ingredients (APIs) from the use of medications. On-label (approved) doses for many drugs can be substantially reduced. Lower doses can reduce the excretion of API residues as well as the generation of medication waste (because of improved patient compliance).

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Why is it important?

Substantial collateral benefits are possible, including the improvement of therapeutic outcomes, reduction of patient expense, and the reduction of mediation waste (which avoids the subsequent need for disposal).

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This page is a summary of: Lower-dose prescribing: Minimizing “side effects” of pharmaceuticals on society and the environment, The Science of The Total Environment, January 2013, Elsevier,
DOI: 10.1016/j.scitotenv.2012.10.092.
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