What is it about?

Ellagic acid directly and selectively targets mitochondria in cancerous B-lymphocytes. • Ellagic acid selectively increases mitochondrial ROS in cancerous B-lymphocytes. • Ellagic acid selectively releases mitochondrial cyt C in cancerous B-lymphocytes. • Ellagic acid can act as an anti-cancer candidate in CLL by selectively inducing apoptosis through mitochondrial pathway.

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Why is it important?

Ellagic acid directly and selectively targets mitochondria in cancerous B-lymphocytes. • Ellagic acid selectively increases mitochondrial ROS in cancerous B-lymphocytes. • Ellagic acid selectively releases mitochondrial cyt C in cancerous B-lymphocytes. • Ellagic acid can act as an anti-cancer candidate in CLL by selectively inducing apoptosis through mitochondrial pathway.

Perspectives

Importance for cancer therapy and prevention

Dr Ahmad Salimi
Adrbabil university of medical sciences

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This page is a summary of: Ellagic acid, a polyphenolic compound, selectively induces ROS-mediated apoptosis in cancerous B-lymphocytes of CLL patients by directly targeting mitochondria, Redox Biology, December 2015, Elsevier,
DOI: 10.1016/j.redox.2015.08.021.
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