What is it about?

Review article, with update on clinical presentation, radiological features and outcomes of ODS in children

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Why is it important?

There is no gender preponderance in children with ODS Its highest prevalence is noted between the ages of 1 and 5 years. Article shows the importance of diffusion tensor imaging in prognostication in ODS. Outcome of ODS in children is favorable with 60% children achieving complete neurological recovery. Current management of ODS in children consists of supportive medical care, steroids and intravenous immunoglobulin. Our review of the literature supports, steroids and immunoglobulins are potentially helpful.

Perspectives

Use of DTI will help identify patients at higher risk for poor long term prognosis and potentially identify candidates which may need more aggressive treatment at the beginning of the illness.

Dr Lalit Bansal
Nicklaus Children's Hospital

Read the Original

This page is a summary of: Osmotic Demyelination Syndrome in Children, Pediatric Neurology, March 2019, Elsevier,
DOI: 10.1016/j.pediatrneurol.2019.03.018.
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