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Ketamine attenuated the excitatory postsynaptic responses evoked by vagal nerve stimulation in a concentration-dependent manner. Ketamine inhibits cholinergic synaptic transmission in the rat intrinsic cardiac ganglia accounting for attenuation of vagal bradycardia.
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This page is a summary of: Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ, Neuropharmacology, March 2020, Elsevier,
DOI: 10.1016/j.neuropharm.2019.107932.
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