What is it about?
Our study reveals that brain changes in autism impact gray matter volume (GMV) and gray matter concentration (GMC) differently across various brain regions. These distinct patterns are not static but shift with age, suggesting that the underlying brain mechanisms in autism evolve over time. This highlights the importance of studying GMV and GMC separately to fully understand autism’s complexity and how it affects the brain at different stages of life. By doing so, future research can better target treatments and interventions that address the specific needs of individuals with autism as they age.
Featured Image
Photo by Milad Fakurian on Unsplash
Why is it important?
This study uniquely clarifies long-standing confusion in autism research by separating gray matter volume (GMV) and concentration (GMC) changes. It reveals distinct brain patterns that evolve with age, paving the way for more targeted and effective interventions in ASD.
Perspectives
From my perspective, this research highlights the complexity of brain changes in autism. By separating gray matter volume (GMV) and concentration (GMC), we see how each plays a distinct role in ASD, varying across brain regions and age. This shift in focus could bring us closer to understanding the underlying mechanisms of autism, and ultimately, improve interventions. It’s exciting to think that this approach might offer clearer insights into the brain and help refine treatments that truly address the needs of individuals with ASD throughout their lives.
Dr. Masaru Tanaka
Szegedi Tudomanyegyetem
Read the Original
This page is a summary of: Disentangling the role of gray matter volume and concentration in autism spectrum disorder: A meta-analytic investigation of 25 years of voxel-based morphometry research, Neuroscience & Biobehavioral Reviews, September 2024, Elsevier,
DOI: 10.1016/j.neubiorev.2024.105791.
You can read the full text:
Contributors
The following have contributed to this page
