What is it about?
This paper shows that polylactide and polycaprolactone enhance selected biological properties of human umbilical cord mesenchymal stem cells (hUC-MSCs). We have demonstrated that the physicochemical properties of PLA and PCL surfaces impacted the proliferation, motility and differentiation potential of hUC-MSCs in vitro.
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Why is it important?
Our findings show that PLA and PCL substrates may enhance spontaneous angiogenic differentiation of hUC-MSCs without additional chemical stimuli.
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This page is a summary of: Polylactide- and polycaprolactone-based substrates enhance angiogenic potential of human umbilical cord-derived mesenchymal stem cells in vitro - implications for cardiovascular repair, Materials Science and Engineering C, August 2017, Elsevier,
DOI: 10.1016/j.msec.2017.03.281.
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