Expanding hyperbranched polyglycerols on hydroxyapatite nanocrystals via ring-opening multibranching polymerization for controlled drug delivery system

Long Giang Bach, Md. Rafiqul Islam, Kwon Taek Lim
  • Materials Letters, February 2013, Elsevier
  • DOI: 10.1016/j.matlet.2012.11.051

Expanding hyperbranched polyglycerols on hydroxyapatite nanocrystals

What is it about?

Hyperbranched polyglycerols (HPG) were covalently grown from hydroxyapatite nanocrystals (HAP NCs) via surface-initiated anionic ring-opening multibranching polymerization (SI-AROMP) of glycidol

Why is it important?

A model drug ibuprofen (IBU) was employed to evaluate the drug loading/release behavior of the HPG-g-HAP nanocomposites. In vitro IBU release profile suggested the nanocomposites as a promising drug delivery system (DDS).


Dr Long Giang Bach
Nguyen Tat Thanh University

Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. This article also lead to rare disease groups contacting me and ultimately to a greater involvement in rare disease research.

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The following have contributed to this page: Dr Long Giang Bach