What is it about?
The cellular response of blood and hepatic tissue to 2, 4 and Gy of γ- irradiation. Serum levels of pro-inflammatory cytokines were significantly elevated in addition to up-regulation of the hepatic NF-кB and down-regulation of p53 and p21 in irradiated groups.
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Why is it important?
Elevated levels of hepatic NF-κB mRNA and low levels of p53 mRNA prove lack of apoptosis and induction of the inflammatory pathway in hepatic cells to face the harmful effects of the present γ-irradiated model.
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This page is a summary of: Cellular response of blood and hepatic tissue to gamma irradiation, Journal of Radiation Research and Applied Sciences, July 2016, Elsevier,
DOI: 10.1016/j.jrras.2015.12.001.
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