Use of strong opioids in advanced cancer pain: a randomized trial

Franco Marinangeli, Alessandra Ciccozzi, Marco Leonardis, Luca Aloisio, Anna Mazzei, Antonella Paladini, Giampiero Porzio, Paolo Marchetti, Giustino Varrassi
  • Journal of Pain and Symptom Management, May 2004, Elsevier
  • DOI: 10.1016/j.jpainsymman.2003.10.006

Strong opioids in cancer pain

What is it about?

Following the WHO guidelines of the 1980', cancer pain should always be treated with a precise escalation sequence of drugs. This study tries to show a different way to look at the problem, also to increase the quality of life of the patients and their relatives.

Why is it important?

It is a very practical support for clinicians involved in cancer pain management


Professor Giustino Varrassi
Paolo Procacci Foundation

This paper was conceived to answer a simple question: Is the WHO analgesic ladder still valid? Our idea was that in many cases the pharmacological treatment of the cancer pain patients should be strategically different, to increase the quality of the care and the quality of life for the patients and their relatives.

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The following have contributed to this page: Professor Giustino Varrassi