What is it about?

This is a study that assessed the effects of tDCS, a neuromodulation technique, On fatigue encountered in multiple sclerosis (MS). tDCS consists of applying weak current of 1-2 mA over the scalp. Compared to placebo, tDCS was able to modulate the brain activity and improve fatigue perception in patients with multiple sclerosis.

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Why is it important?

The available medications for MS fatigue are faced with limited benefits and several side-effects. In this perspective, modulating the brain activity via tDCS for example could be of help to relieve various neuropsychiatric symptoms, such as fatigue in MS.

Perspectives

The importance of this work lies in its comparative aspect. In this randomized, sham-controlled clinical trial, We applied tDCS over two different brain regions: the right posterior parietal cortex and the left dorsolateral prefrontal cortex. Only the later was able to decrease fatigue perception in MS patients.

Dr Moussa Antoine Chalah
Universite Paris-Est Creteil Val de Marne

Read the Original

This page is a summary of: Effects of left DLPFC versus right PPC tDCS on multiple sclerosis fatigue, Journal of the Neurological Sciences, January 2017, Elsevier,
DOI: 10.1016/j.jns.2016.11.015.
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