The blood brain barrier in vascular dementia

What is it about?

According to Davson definition, the blood brain barrier is the sum of all bidirectional exchange processes that occur in the morphological blood brain interfaces. The morphological background of the blood brain consists of the highly specialized endothelial cells and their tight junctions and the perivascular structural adjuncts, such as the pericytes, the microglia and the astrocytes, which interact in the homeostatic processes between the blood and the brain parenchyma. In a considerable number of brains from patients who suffered from vascular dementia we attempted to study the brain capillaries in various parts of the cortex of the brain hemispheres and the cerebellum, using silver impregnation techniques.

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