What is it about?

obese patients treated with UDCA before surgery showed changes in lipid homeostasis and bile acid signaling by UDCA antagonizing FXR

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Why is it important?

a new research showing that FXR modulation by endogenous bile acids is possible in morbid obese

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This page is a summary of: Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity, Journal of Hepatology, June 2015, Elsevier,
DOI: 10.1016/j.jhep.2014.12.034.
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