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The purpose was to describe the use of valproate therapy for agitation in critically ill patients, examine its safety, and describe its relationship with agitation and delirium. Valproate therapy was associated with a reduction in agitation, delirium, and concomitant psychoactive medication use within 48 hours of initiation.

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This page is a summary of: Valproate for agitation in critically ill patients: A retrospective study, Journal of Critical Care, February 2017, Elsevier,
DOI: 10.1016/j.jcrc.2016.09.006.
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