What is it about?
Proposing a concentration gradient induced peptide desorption model system. Revealing desorption features and mechanisms of peptide assemblies on solids. Unravelling key effect of substrate, humidity, and others on peptide desorption. Quantifying the desorption exponential kinetics with an index of one-half. Highlighting the knowledge gap between nanoscale and micro-/macroscales.
Featured Image
Why is it important?
Self-assembled monolayers of biomolecules, particularly peptides, are important for a wide range of applications, including surface coatings, biosensing, and bioelectronics. The performance of peptide two-dimensional crystal patterns on solid substrates as molecular scaffolds strongly depends on the stability of the assemblies, which is closely related to their desorption behavior. However, investigation on peptide desorption remains poorly understood, especially across distinct sizes and time scales.
Perspectives
This work provides fundamental insight into CG-induced peptide desorption on graphite surfaces and helps bridge the knowledge gap between nanoscale desorption phenomena and behavior at micro‐−/macroscales. It also highlights the potential applications of peptide-based systems in self-cleaning surfaces, controllable release, and related technologies.
Linhao Sun
Kanazawa Daigaku
Read the Original
This page is a summary of: Soft-interfacial concentration gradients drive size-/time-scale desorption characteristics and mechanisms of dodecapeptide assemblies, Journal of Colloid and Interface Science, December 2026, Elsevier,
DOI: 10.1016/j.jcis.2026.141191.
You can read the full text:
Contributors
The following have contributed to this page
