Genome wide transcription start sites analysis of Xanthomonas campestris pv. campestris B100 with insights into the gum gene cluster directing the biosynthesis of the exopolysaccharide xanthan

  • Rabeaa S. Alkhateeb, Frank-Jörg Vorhölter, Christian Rückert, Almut Mentz, Daniel Wibberg, Gerd Hublik, Karsten Niehaus, Alfred Pühler
  • Journal of Biotechnology, May 2016, Elsevier
  • DOI: 10.1016/j.jbiotec.2016.03.020

Identification of Xanthomonas campestris transcription start sites by RNA-seq

What is it about?

RNA-seq has been applied to Xanthomonas campestris pv. campestris, a model organism for pant pathogenic bacteria and producer of the polysaccharide xanthan, to globally determine transcription start sites. This is the first such analysis for a bacterium of the genus Xanthomonas.

Why is it important?

Knowledge of transcription start sites greatly facilitates systematic recognition of promoter sites, which are crucial for the regulation of gene expression. This data is a valuable basis that will facilitate the analysis of regulatory processes in Xanthomonas bacteria, where such regulation is so far only poorly conceived.

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The following have contributed to this page: Dr Frank Jörg Vorhölter