What is it about?

Normal collagen molecules form triple helix structures. We immobilized a synthetic collagen model peptide and developed a sensor that can detect only normal collagen that can form triple helix structures.

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Why is it important?

The collagen model peptide immobilized sensor we are proposing for the first time is a simple sensor that guarantees the quality of collagen. Collagen has a triple helix structure in which characteristic amino acid sequences are repeated. Collagen with defective molecular sequences or fragmented low molecular weight collagen does not form a triple helix structure and does not exhibit collagen functions. Therefore, this sensor, which guarantees the quality of collagen, is considered adequate in the food industry and pharmaceutical fields.

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This page is a summary of: Quartz crystal microbalance sensor for the detection of collagen model peptides based on the formation of triple helical structure, Journal of Bioscience and Bioengineering, February 2022, Elsevier,
DOI: 10.1016/j.jbiosc.2021.11.006.
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