What is it about?
Synthesis and microbiologic studies of a regioselectively substituted beta-cyclodextrin.
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Why is it important?
Inactivation of pore-forming proteins adds adjuvant effect to antibiotics.
Perspectives
Blocking of pores can inhibit the spreading of toxins or prevent the leakage of important cell constituents, like corks in the bottle.
Dr Laszlo Jicsinszky
University of Turin, DSTF
Read the Original
This page is a summary of: Inhibition of Clostridium perfringens epsilon toxin by β-cyclodextrin derivatives, International Journal of Pharmaceutics, October 2017, Elsevier,
DOI: 10.1016/j.ijpharm.2017.07.070.
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