What is it about?
Curcumin is a "star" anticancer molecule with the background of plant extract. However, its instability, low solubility, and rapid metabolism make it difficultly become a "true" anticancer agent. In this study, an in situ curcumin hydrogel is prepared with combination of cyclodextrin complex technique. Its properties are well explored.
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Why is it important?
A new research direction of curcumin after overcoming its disadvantages and using alternative administration routes.
Perspectives
Transdermal and other local applications of curcumin are a promising strategy for development of this known anticancer agent.
Dr. Yiguang Jin
Beijing Institute of Radiation Medicine
Read the Original
This page is a summary of: Transdermal delivery of the in situ hydrogels of curcumin and its inclusion complexes of hydroxypropyl-β-cyclodextrin for melanoma treatment, International Journal of Pharmaceutics, July 2014, Elsevier,
DOI: 10.1016/j.ijpharm.2014.04.039.
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