What is it about?
This paper reports the discovery of the transcription factor protein called PAX5 that regulates the production of the Mucolipin-2 (TRPML2) protein. The paper also identified the strand of DNA where the PAX5 protein binds and start the transcription of the Mucolipin-2 gene.
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Why is it important?
The findings showed how the Mucolipin-2 is regulated and pinpoints to the type of cells the protein is expressed based on the identity of the transcription factor known as PAX5.
Read the Original
This page is a summary of: PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene, Gene, January 2015, Elsevier,
DOI: 10.1016/j.gene.2014.11.003.
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