What is it about?
Human gut flora from lean and obese individuals metabolize non-digestible fraction of spent coffee grounds (hgf-NDSCG) through different chemopreventive mechanisms. Overweight/hgf-NDSCG displayed cytostatic and cytotoxic effects on HT-29. Lean/hgf-NDSCG induced HT-29 cell apoptosis by reducing oxidative stress.
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Why is it important?
Our study demonstrate that the chemopreventive effect of novel functional food product/s (SCG) is dependent on individual (lean vs obese) metbolomics.
Perspectives
Food products can be developed to target consumers with different BMI
Dr B. Dave Oomah
Formerly with AAFC
Read the Original
This page is a summary of: Microbiota source impact in vitro metabolite colonic production and anti-proliferative effect of spent coffee grounds on human colon cancer cells (HT-29), Food Research International, July 2017, Elsevier,
DOI: 10.1016/j.foodres.2017.04.004.
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