What is it about?
In this review, we outline the scientific requirements identified by the Innovative Medicines Initiative (IMI) Open PHACTS consortium for the design of an open pharmacological space (OPS) information system. Typical scientific competency questions provided by the consortium members is analyzed based on the underlying data concepts and associations needed to answer the questions.
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Why is it important?
In the design of a system for scientists interested in querying complex datasets to answer questions regarding pharmacology it is necessary to consider what some of those questions might be way ahead of time. This paper discusses the methodology of gathering that input as well as the resulting question set and should be of interest to anyone building similar systems in the future. Spend your time upfront gathering the appropriate user input rather than build it and they will come!
Read the Original
This page is a summary of: Scientific competency questions as the basis for semantically enriched open pharmacological space development, Drug Discovery Today, September 2013, Elsevier,
DOI: 10.1016/j.drudis.2013.05.008.
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Resources
Summary view of data sources, content and data concepts that are of interest for an open pharmacological space
Summary view of data sources, content and data concepts that are of interest for an open pharmacological space, recorded in March 2012. Emphasized is the open and free public access of the data sources
The Open PHACTS Explorer
The Open PHACTS Explorer allows multiple sources of publicly-available pharmacological and physicochemical data to be intuitively queried, and makes data provenance accessible at every step. The Open PHACTS Explorer was built to answer critical pharmacological questions as defined by academic and pharmaceutical industry scientists.
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