What is it about?

The study, published in late 2025, announced the discovery of three unique SNPs in the P. falciparum isolates from Kogi.

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Why is it important?

These new variations underscore the importance of monitoring malaria parasite genetics in Africa, as understanding these mutations helps track potential antimalarial resistance.

Perspectives

A recent study identified three novel single nucleotide polymorphisms (SNPs) in Plasmodium falciparum parasites from Kogi State, Nigeria, highlighting ongoing genetic diversity and the need for continuous surveillance, especially concerning drug resistance markers like those in the K13 propeller gene, as these variations can impact malaria treatment effectiveness and vaccine development, with researchers often looking at genes like msp1, msp2, and glurp.

Onyekachi Nnaemeka Akoma
University of Nigeria Nsukka

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This page is a summary of: Three New Single Nucleotide Polymorphisms Identified in Plasmodium falciparum Isolates from Kogi State, Nigeria, Diagnostic Microbiology and Infectious Disease, December 2025, Elsevier,
DOI: 10.1016/j.diagmicrobio.2025.117233.
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