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In silico genome translation defines amino acid ratios for exome-matched diets. Exome-matched diets reduce ad libitum food intake in flies and mice. Exome-matched diets enhance early life fitness in flies without lifespan cost. Improved mouse growth on an exome-matched diet demonstrates its utility for mammals.

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This page is a summary of: Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan, Cell Metabolism, March 2017, Elsevier,
DOI: 10.1016/j.cmet.2017.02.005.
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