Factors Predicting Adherence to a Tailored-Dose Adjuvant Treatment on the Basis of Geriatric Assessment in Elderly People With Colorectal Cancer: A Prospective Study

What is it about?

• Selecting elderly CRC patients for adjuvant therapy remains a challenge. Comprehensive geriatric assessment (CGA) is useful for defining multiple frailty levels and guiding decision-making. • The supposed benefit of adjuvant chemotherapy is related to the rate of treatment adherence. • To identify factors associated with elderly patient’s refusal, toxicity and treatment completion can improve adherence to adjuvant chemotherapy.

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Why is it important?

CGA is useful for selecting elderly patients for adjuvant chemotherapy, adapting the dose to their frailty profile. CGA can and identify adherence-related factors amenable to modification through CGA-based interventions.