What is it about?
A new aptamer-based biosensor has been synthesized. The sensor measures intracellular concentrations of fructose 1,6-bisphosphate. which is a key metabolite in all cell types.
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Why is it important?
Measurements of fructose 1,6-bisphosphate can reveal how much sugar (glucose) is consumed in the cells
Perspectives
The sensor is the fifth sensor developed in my laboratory. The other sensors measure: 1. Reactive oxygen species 2. Glucose 3. ATP 4. Inositol triphosphate
Lars Folke Olsen
Syddansk Universitet
Read the Original
This page is a summary of: A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux, Cell Chemical Biology, April 2021, Elsevier,
DOI: 10.1016/j.chembiol.2021.04.006.
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