What is it about?

Lycopene was able to inhibit the production of ROS in vitro and A Single dose of lycopene mitigate the damage caused by APAP overdose in vivo.

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Why is it important?

Hepatoprotective effect of a single dose lycopene in animal models.

Perspectives

Further experiments need to be performed in order to concretely establish the hepatoprotective effect of lycopene in animal models. Thus, The next goal will be to check the effect of prolonged pretreatment rather than just a single dose of lycopene

Dr Daniela Costa
UFOP

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This page is a summary of: Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice, Chemico-Biological Interactions, February 2017, Elsevier,
DOI: 10.1016/j.cbi.2016.12.011.
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