What is it about?
This study aims to review phytol (PYT), through published articles, periodicals, magazines and patents, which were retrieved from the PM, SD, WS, SP; DII, WIPO, CIPO, USPTO and INPI databases.
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Why is it important?
In the pharma-medico viewpoint, phytol and its derivatives have been evident to have antimicrobial, cytotoxic, antitumorous, antimutagenic, anti-teratogenic, antibiotic-chemotherapeutic, antidiabetic, lipid lowering, antispasmodic, anticonvulsant, antinociceptive, antioxidant, anti-inflammatory, anxiolytic, antidepressant, immunoadjuvancy, hair growth facilitator, hair fall defense and antidandruff activities. Otherwise, the important biometebolite of phytol is phytanic acid. Evidence shows phytanic acid to have cytotoxic, anticancer, antidiabetic, lipid lowering and aniteratogenic activities. In addition, it may be considered as an important biomarker for some diseases such as Refsum's Disease, Sj€ogren Larsson syndrome, rhizomelic chondrodysplasia punctata, chronic polyneuropathy, Zellweger's disease hyperpipecolic academia and related diseases.
Perspectives
Phytol may be considered as a new drug candidate.
Dr. Muhammad Torequl Islam
Read the Original
This page is a summary of: Phytol in a pharma-medico-stance, Chemico-Biological Interactions, October 2015, Elsevier,
DOI: 10.1016/j.cbi.2015.07.010.
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