What is it about?

Characterization of the effect of HDACi on the expression of genes involved in calcium homeostasis

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Why is it important?

The decreased expression of ATP2A3 gene correlates with high mortality in hepatocellular carcinoma patients. This work provide insights into how to increase ATP2A3 expression to improve survival

Perspectives

To develop strategies to modulate the expression of altered genes in hepatocellular carcinoma

PhD Eduardo Izquierdo Torres
Universidad Nacional Autonoma de Mexico

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This page is a summary of: Histone deacetylase inhibitors promote ATP2A3 gene expression in hepatocellular carcinoma cells: p300 as a transcriptional regulator, The International Journal of Biochemistry & Cell Biology, August 2019, Elsevier,
DOI: 10.1016/j.biocel.2019.05.014.
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