What is it about?
Identification of the first Tuberculosis Topisomerase I inhibitor.
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Why is it important?
Likely the first paper to describe m-AMSA as a Topoisomerase I inhibitor. using computational and in vitro approaches.
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This page is a summary of: Inhibition of Mycobacterium tuberculosis topoisomerase I by m-AMSA, a eukaryotic type II topoisomerase poison, Biochemical and Biophysical Research Communications, April 2014, Elsevier,
DOI: 10.1016/j.bbrc.2014.03.029.
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