What is it about?
It looks not only at reasons for underutilization of influenza vaccines, but validity of those reasons. It looks at past experience of influenza infections and past experience of vaccination. It examined efficacy of intranasal versus injectible vaccines for the study season, and possible effect of birth month on utilization. The biggest determinant of benefit from vaccination was past history of influenza infection, reflecting probable variance in individual susceptibility to infection.
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Why is it important?
Better influenza vaccines are needed and more needs to be learned about genetically determined variability in influenza susceptibility.
Perspectives
Many areas of needed research are identified, including determining actual frequency with which individuals experience significant influenza pathology in relationship with individual vaccination history, exploring innate influenza resistance mechanisms and prevalence, determining vaccine efficacy for duration of protection, and improving potential protection with novel vaccines.
Dr Scott S. Field
UAB School of Medicine
Read the Original
This page is a summary of: Reasons for influenza vaccination underutilization: A case-control study, American Journal of Infection Control, October 2016, Elsevier,
DOI: 10.1016/j.ajic.2016.05.021.
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