What is it about?
The purpose of this review is to present the current state of knowledge related to the risks of the engineered nanoparticles and how to assess the various properties by application of theoretical and computational methods, applicable for evaluation of nanomaterials.
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Why is it important?
Because of nanomaterials intrinsic properties, they are commonly employed in electronics, photovoltaic, catalysis, environmental and space engineering, cosmetic industry and – finally – in medicine and pharmacy. In that sense, nanotechnology creates great opportunities for the progress of modern medicine. However, recent studies have shown evident toxicity of some nanoparticles to living organisms (toxicity), and their potentially negative impact on environmental ecosystems (ecotoxicity). Lack of available data and low adequacy of experimental protocols prevent comprehensive risk assessment.
Perspectives
This is state-of-the-art review that discussed how computationally can be estimated various properties of nanomaterials, including toxicity, in order to assess the risks connected with them, by avoiding experiments with animal use.
Professor Bakhtiyor Rasulev
North Dakota State University
Read the Original
This page is a summary of: Advancing risk assessment of engineered nanomaterials: Application of computational approaches, Advanced Drug Delivery Reviews, December 2012, Elsevier,
DOI: 10.1016/j.addr.2012.05.014.
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