Nanoparticles of alkylglyceryl-dextran- graft -poly(lactic acid) for drug delivery to the brain: Preparation and in vitro investigation

Petr Toman, Chun-Fu Lien, Zeeshan Ahmad, Susanne Dietrich, James R. Smith, Qian An, Éva Molnár, Geoffrey J. Pilkington, Darek C. Górecki, John Tsibouklis, Eugen Barbu
  • Acta Biomaterialia, September 2015, Elsevier
  • DOI: 10.1016/j.actbio.2015.05.009

Making nanoparticles that penetrate the blood-brain-barrier to treat brain diseases

What is it about?

Formation and characterisation of modified dextran nanoparticles and an investigation of their performance to penetrate the blood-brain-barrier

Why is it important?

Producing nanoparticles that deliver drugs to the brain is becoming increasingly attractive. Nanoparticles can be designed to pass across the blood-brain-barrier and so deliver the relevant drug directly to the brain.

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http://dx.doi.org/10.1016/j.actbio.2015.05.009

The following have contributed to this page: Dr James R Smith