What is it about?
DNaseI foot printing may be done using fragment analysis on a DNA sequencer. This methods update provides an optimized workflow that avoids technical problems and pitfalls inherent to the technique.
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Why is it important?
If not performed accurately, incomplete or even misleading information may be obtained, compromising interpretation.
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This page is a summary of: A recommended workflow for DNase I footprinting using a capillary electrophoresis genetic analyzer, Analytical Biochemistry, July 2015, Elsevier,
DOI: 10.1016/j.ab.2015.04.013.
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