What is it about?

Type 1 diabetes and LADA are autoimmune diseases with loss of immune tolerance. Vitamin D3 has immunoregulatory properties with effects on Treg cells, improving its number and functions , thereby restoring immune tolerance, and acting on beta cells improving their function and reducing their apoptosis.

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Why is it important?

Low-cost and almost no side effects, vitamin D3 is an excellent option to be associated with other immunomodulatory medications, such as DPP-4 inhibitors to promote prolonged remission of type 1 diabetes and LADA.

Perspectives

Vitamin D3 is an excellent option to be associated with other immunomodulatory medications, such as DPP-4 inhibitors to promote prolonged remission of type 1 diabetes and LADA.

MD,PhD MARCELO MAIA PINHEIRO
Univag - University Center

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This page is a summary of: Vitamin D3 in the Type 1 Diabetes and Latent Autoimmune Diabetes in Adults, Its Use for Prevention and Treatment, January 2019, Elsevier,
DOI: 10.1016/b978-0-12-813822-9.00011-4.
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