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The local tissue (anus + rectum) levels after application of tribenosite. This local availability was shown to be high in comparison with the systemic availability in rats.

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This delivery system is marketed in Japan (

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This page is a summary of: Assessment of local and systemic availability of tribenoside after rectal administration in rats, International Journal of Pharmaceutics, July 1980, Elsevier,
DOI: 10.1016/0378-5173(80)90028-9.
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