What is it about?

To determine the effectiveness and safety of high-dose isoxsuprine for the treatment of mixed-type erectile dysfunction (impotence).

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Why is it important?

everal treatment options for organic impotence have been developed that do not require surgery, such as sexual counseling, pharmacologic intracavernous injection programs, penile vacuum devices, and the use of oral pharmacologic agents. The treatment of choice for impotence today is nonspecific therapy with self-injected vasoactive agents. This treatment is effective, but it is not possible in all cases. Many patients find the idea of giving themselves injections, especially into the penis, extremely difficult. Pharmacologic drug-induced erections have been found to have side effects and complications. We need effective noninvasive methods of treating impotence, such as oral medication or locally applicable preparations.


Although a more selective and effective drug, sildenafil, is available for the noninvasive treatment of this condition, other drugs are also needed

Dr Mohammad Reza Safarinejad
University of Medical Sceices

Read the Original

This page is a summary of: Therapeutic effects of high-dose isoxsuprine in the management of mixed-type impotence, Urology, July 2001, Elsevier,
DOI: 10.1016/s0090-4295(01)01084-6.
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