What is it about?

How far unilateral pedicle screw fixation is a reliable mode of fixation of two-level degenerative disorders of the spine

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Why is it important?

We performed this meta-analysis to compare the safety of unilateral with bilateral instrumented fusion in two-level degenerative disorders of lumbar spine.


Our meta-analysis establishes the immediate safety and significant lesser operative period of unilateral pedicle screw fixation in lumbar fusion. However, due to lack of evidence on complications like cage subsidence and adjacent segment disease, unilateral pedicle screw fixation cannot be recommended as an alternative to bilateral pedicle screw fixation for two-level degenerative spinal disease. Our analysis established the lacunae in literature for high-quality evidence on the subject hence we recommend further large multicentre studies with longer follow-up to arrive at a conclusion.

Dr Sathish Muthu
Government Hospital, Velayuthampalayam, Karur, TN, India.

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This page is a summary of: How Safe is Unilateral Pedicle Screw Fixation in Lumbar Fusion Surgery for Management of Two-level Lumbar Degenerative Disorders compared to Bilateral Pedicle Screw Fixation ? A Meta-analysis of Randomised Control Trials, World Neurosurgery, May 2020, Elsevier,
DOI: 10.1016/j.wneu.2020.05.078.
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