What is it about?
We describe how a racemic mixture of fire ant pyridine and piperidine alkaloids can be obtained by synthesis using a compound readily available from Sigma-Aldrich, named 2,6-Lutidine. Next, we describe a method using a chiral column to assess their isomeric proportions, and illustrate their variation among fire ant castes in two populations in Brazil.
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Why is it important?
The described method for the synthesis of the fire ant alkaloids is fairly simple for a chemistry facility. The described method opens the doors to a number of developments in this field of research. This is exampled in the present paper by a direct application to assess isomeric proportions as to understand the natural biochemical synthesis of fire ant alkaloids and their taxonomic utility.
Read the Original
This page is a summary of: Rapid configuration analysis of the solenopsins, Tetrahedron Asymmetry, May 2012, Elsevier, DOI: 10.1016/j.tetasy.2012.05.005.
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Precioso Veneno [Precious Venom]
A short interview given to a local science news magazine [in Portuguese] about the importance of fire ant venom and extraction method.
Das Moléculas aos organismos [From molecules to living beings]
An interview provided by the senior author of this paper regarding the biotech importance of natural compounds including these alkaloids herein described.
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