What is it about?

Our aim was to describe prevalence of signs of executive function deficits and primitive reflexes in older inpatients and their discriminant value for delirium while accounting for dementia.

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Why is it important?

When comorbid, delirium symptoms overshadow those of the underlying dementia, and delirium should be diagnosed and managed as the urgent clinical priority. Clinicians are in the need for bedside signs for delirium diagnosis, especially when it is comorbid to dementia.


PR and EF deficit signs (Frontal Delirium Index) are consistent with reduced neural network integration during delirium, even worse in those with dementia whose baseline structural injury impairs network connectivity with frontal regions.

Universidad Pontificia Bolivariana

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This page is a summary of: Discriminant Performance of Dysexecutive and Frontal Release Signs for Delirium in Patients With High Dementia Prevalence: Implications for Neural Network Impairment, Psychosomatics, April 2020, Elsevier,
DOI: 10.1016/j.psym.2020.04.002.
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