What is it about?
It enhances cell culture performance - increasing cell viability and decreasing sialic acid removal.
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Why is it important?
Biologics with higher level of sialic acid can stay in blood for longer time.
Perspectives
LongR3 (insulin-like growth factor) is becoming a routine cell culture performance enhancer.
Dr Yueming Qian
Bristol-Myers Squibb Co
Read the Original
This page is a summary of: LongR3 enhances Fc-fusion protein N-linked glycosylation while improving protein productivity in an industrial CHO cell line, Process Biochemistry, February 2017, Elsevier,
DOI: 10.1016/j.procbio.2016.11.018.
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