What is it about?

This study explored the therapeutic potential of TCM to complement standard T1D treatment and considered perspectives from both TCM and modern medicine on pathophysiology and management. While preclinical studies and limited clinical evidence suggest TCM's potential and wide-ranging effects in early-stage T1D intervention and its complications, there is a need for more translational research and clinical trials to address current gaps.

Featured Image

Why is it important?

T1D presents challenges in managing diabetes and maintaining glycemic control. Many patients develop diabetic complications within five years of disease onset. Although insulin therapy is currently the most effective treatment, most patients do not achieve target glycemic control or fully benefit from it, even with AID systems, as recent CGMS studies indicate. Therefore, the best approach is to prevent or delay the pathophysiological development of T1D during its early stages. However, aside from CD3 monoclonal antibody treatment, which is available on the market, there are few effective therapies, even though early detection in stages 1-2 is becoming more feasible with advancing methodologies and laboratory technologies. This early window offers significant opportunities for interventions to protect β-cells and prevent immune damage to the islets. This study explores the potential of TCM as an adjunct therapy in the comprehensive management of T1D.

Perspectives

Current evidence suggests that early diagnosis and intervention are essential for TID management, but it does not support the feasibility of TCM in TID treatment. There is still a long way to go before implementing these from research to clinical applications.

Dr. Song Wen
Shanghai Pudong Hospital, Fudan University

Read the Original

This page is a summary of: Therapeutic Values of Traditional Chinese Medicine (TCM) in Evolution of Type 1 Diabetes Mellitus with Its Microvascular Complications in Adults, Pharmacological Research - Modern Chinese Medicine, May 2026, Elsevier,
DOI: 10.1016/j.prmcm.2026.100826.
You can read the full text:

Read

Resources

Contributors

The following have contributed to this page