What is it about?
Globally, gynecological complications such as menorrhagia and dysmenorrhea lack attention. We aim to corroborate original ethno-phytomedicine data that was prescribed for menorrhagia and dysmenorrhea treatment, by studying the evidence-based therapeutic efficacy of medicinal plants and the potential role of gut microbiota in relevant phytopharmacology.
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Why is it important?
As traditional phytomedicines are suffering from a lack of standardization parameters compared to modern synthetic drugs, the implementation of advanced technologies and emerging scientific strategies can significantly impact the scientific validity, quality, and standardization of traditional herbal medicines. The present study suggests further biological research towards a more updated standardized phytomedicine formulation that can effectively treat menorrhagia and dysmenorrhea.
Perspectives
1) Gut dysbiosis and/or estrobolome dysfunctions can lead to either a deficiency or an increase of free estrogen resulting in estrogen-related pathologies. 2) Catechin present in Acacia catechu and Piper nigrum may exhibit aromatase and β-glucuronidase inhibitory activity to balance estrogen levels in patients suffering from menorrhagia and dysmenorrhea. 3) The impacts of the prescribed phytomedicine on estrobolome disruption need to be validated in scientific studies including optimization of the ratio between the three plant parts used by the traditional practitioner.
Md Nasir Ahmed
University of Development Alternative
Read the Original
This page is a summary of: Evaluation of herbal ingredients used in an ethno-polyherbal formulation for treating menorrhagia and dysmenorrhea in Bangladesh, Phytomedicine Plus, November 2022, Elsevier,
DOI: 10.1016/j.phyplu.2022.100366.
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